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levoketoconazole will improve the degree or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.nelfinavir will raise the degree or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.nefazodone will increase the level or result of modafinil by affecting hepati